Griffonia seed is a natural source of 5-HTP, an amino acid that helps the body make serotonin. Serotonin is an important neurotransmitter that plays a major role in sleep, pain, and appetite. It influences pain thresholds by interacting with other compounds involved in the sensation of pain, like substance P and endorphins. Disruptions in serotonin metabolism have been reported as a hallmark characteristic of fibromyalgia, with fibromyalgia patients showing marked reductions in serotonin levels.